| Updates of adjuvant therapy in pancreatic cancer: where are we and where are we going? Highlights from the "2010 ASCO Annual Meeting". Chicago, IL, USA. June 4-8, 2010. | |
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MedLine Citation:
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PMID: 20601799 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pancreatic cancer represents the 4th leading cause of cancer deaths in the United States. Surgical resection remains the only potential curative approach. Current standard adjuvant therapy is gemcitabine monotherapy for 6 months. This year several trials investigated other combinations with or without molecular target agents, with or without concurrent radiation attempting to optimize adjuvant therapy. Several abstracts presented at the 2010 American Society of Clinical Oncology (ASCO) Annual Meeting are highlighted here and will be further discussed in this review article. Abstracts #4012, #4059, and TPS226 added immunotherapy to adjuvant treatment. Abstract #4034 demonstrated lack of efficacy by adding either cetuximab or bevacizumab to known adjuvant therapies. Abstract e14625 combined S-1 to gemcitabine and abstract #4113 demonstrated a positive correlation between symptoms and CA 19-9 levels with the length of survival. |
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Authors:
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Jia Li; Man Yee Merl; John Chabot; Muhammad Wasif Saif |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Review Date: 2010-07-05 |
Journal Detail:
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Title: JOP : Journal of the pancreas Volume: 11 ISSN: 1590-8577 ISO Abbreviation: JOP Publication Date: 2010 |
Date Detail:
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Created Date: 2010-07-05 Completed Date: 2010-11-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101091810 Medline TA: JOP Country: Italy |
Other Details:
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Languages: eng Pagination: 310-2 Citation Subset: IM |
Affiliation:
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Yale University School of Medicine, New Haven, CT, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adjuvants, Immunologic
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therapeutic use Carcinoma / therapy* Chemotherapy, Adjuvant / methods Chicago Combined Modality Therapy / methods, trends* Congresses as Topic Humans Immunotherapy / methods Medical Oncology / trends Pancreatic Neoplasms / therapy* Radiotherapy, Adjuvant / methods Societies, Medical United States |
| Chemical | |
Reg. No./Substance:
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0/Adjuvants, Immunologic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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