Document Detail


Updated use of digitalis and nitrates in the elderly.
MedLine Citation:
PMID:  2891589     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Myocardial ischemia may be produced by a wide variety of pathophysiologic scenarios. Currently, long-acting nitrates, beta blockers, and calcium blocking drugs are available to treat ischemia. Each class of therapy poses potential problems for the elderly, and therapy must be individualized. Long-acting nitrates are probably not the best choice of monotherapy since tolerance develops to their use over time. Congestive heart failure, a common sequela to myocardial infarction, is currently best treated by diuretics and vasodilating drugs. These therapies are generally well-tolerated by the elderly. Digitalis, which is not easily given to the elderly due to potential toxicity, is probably best avoided in this patient group unless needed to treat arrhythmia. Careful differential diagnosis of congestive heart failure is a critical pre-condition to starting any therapy for heart failure, particularly in the elderly patient.
Authors:
S R Goldsmith; S Marx
Related Documents :
10487799 - Increasing the impact of cardiological treatments. how best to reduce deaths.
10845239 - Heart failure drugs: what's new?
10422459 - Update on the pharmacological management of congestive heart failure.
16901709 - Doxorubicin in experimental and clinical heart failure.
3154699 - Combination of positive inotropic and vasodilating substances in congestive heart failure.
10089929 - Diagnosis and treatment of diastolic heart failure.
12365559 - Systolic heterogeneity of transmural myocardial function in normal subjects: physiologi...
21892949 - Telemetric left ventricular monitoring using wireless telemetry in the rabbit model.
11673349 - Long-term effects of nonselective endothelin a and b receptor antagonism in postinfarct...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Geriatrics     Volume:  43     ISSN:  0016-867X     ISO Abbreviation:  Geriatrics     Publication Date:  1988 Jan 
Date Detail:
Created Date:  1988-02-17     Completed Date:  1988-02-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  2985102R     Medline TA:  Geriatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  71-2, 75, 78-82 passim     Citation Subset:  AIM; IM    
Affiliation:
Cardiology Clinics, Hennepin County Medical Center, Minneapolis.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Antagonists / therapeutic use
Aged
Calcium Channel Blockers / therapeutic use
Coronary Disease / drug therapy*
Digitalis Glycosides / therapeutic use*
Heart Failure / drug therapy*
Humans
Nitrates / therapeutic use*
Vasodilator Agents / therapeutic use
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Calcium Channel Blockers; 0/Digitalis Glycosides; 0/Nitrates; 0/Vasodilator Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of recA mutations on pilus antigenic variation and phase transitions in Neisseria gonorrhoea...
Next Document:  Dipeptidyl peptidase IV activity in cells of T-lymphoid origin is decreased in cultures with 12-0-te...