Document Detail

Update on the "sick placenta syndrome". Pre-eclampsia: still a difficult disease.
MedLine Citation:
PMID:  8680154     Owner:  NLM     Status:  MEDLINE    
Pre-eclampsia (PE) and eclampsia is the leading cause of maternal death in the UK and a major cause of perinatal morbidity and mortality. PE is predominantly a disorder of first pregnancy. There is a genetic component. PE is a syndrome without a defined cause. The variability with which it presents, and the speed with which it progresses, make it hard to diagnose. High blood pressure and proteinuria, with or without oedema, are classic symptoms but it may also present in an unusual way, eg as jaundice; as proteinuria with normal blood pressure; as intra-uterine growth retardation; as abdominal pain. The placenta becomes "sick" because of restricted blood flow from the mother; an unknown factor causes disturbances to spread throughout the mother's circulation which may lead to blindness, strokes, liver rupture and death. Delivery of the placenta is the only effective treatment, but preventive options being explored include aspirin and calcium supplements.
C Redman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Professional care of mother and child     Volume:  4     ISSN:  0964-4156     ISO Abbreviation:  Prof Care Mother Child     Publication Date:    1994 Jan-Feb
Date Detail:
Created Date:  1996-08-22     Completed Date:  1996-08-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9301173     Medline TA:  Prof Care Mother Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  7-9     Citation Subset:  N    
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MeSH Terms
Pre-Eclampsia* / diagnosis,  epidemiology,  etiology,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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