Document Detail


Update on the pathophysiology and management of idiopathic intracranial hypertension.
MedLine Citation:
PMID:  22423118     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Idiopathic intracranial hypertension is a disease of unknown aetiology, typically affecting young obese women, producing a syndrome of increased intracranial pressure without identifiable cause. Despite a large number of hypotheses and publications over the past decade, the aetiology is still unknown. Vitamin A metabolism, adipose tissue as an actively secreting endocrine tissue and cerebral venous abnormalities are areas of active study regarding the pathophysiology of idiopathic intracranial hypertension. There continues to be no evidence based consensus or formal guidelines regarding management and treatment of the disease. Treatment studies show that the diagnostic lumbar puncture is a valuable intervention beyond its diagnostic importance, and that weight management is critical. However, many questions remain regarding the efficacy of acetazolamide, CSF shunting procedures and cerebral transverse venous sinus stenting.
Authors:
Valérie Biousse; Beau B Bruce; Nancy J Newman
Related Documents :
8149698 - Pulmonary vascular reactivity and ischaemia-reperfusion injury in the rat.
22784888 - Prevention and treatment of orthostatic hypotension in the orthopedic patient population.
3157028 - Protection of the hypertrophied pig myocardium. a comparison of crystalloid, blood, and...
24477488 - Enhanced ionic conductivity in polycrystalline tio2 by "one-dimensional doping"
132688 - Regional lung perfusion and pulmonary artery pressure in chronic obstructive lung disease.
6349388 - Cardiovascular changes from expiration to inspiration during ippv.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2012-03-15
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  83     ISSN:  1468-330X     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-11     Completed Date:  2012-06-12     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  488-94     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Emory University, Atlanta, GA, USA. vbiouss@emory.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Bariatric Surgery / statistics & numerical data
Carbonic Anhydrase Inhibitors / therapeutic use
Humans
Magnetic Resonance Imaging
Obesity / complications*,  surgery
Prevalence
Pseudotumor Cerebri* / complications,  drug therapy,  epidemiology,  physiopathology,  surgery
Grant Support
ID/Acronym/Agency:
K23 EY019341/EY/NEI NIH HHS; K23-EY019341/EY/NEI NIH HHS; KL2 RR025009/RR/NCRR NIH HHS; KL2-RR025009/RR/NCRR NIH HHS; P30 EY006360/EY/NEI NIH HHS; P30-EY06360/EY/NEI NIH HHS; UL1 RR025008/RR/NCRR NIH HHS; UL1-RR025008/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Carbonic Anhydrase Inhibitors
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Depression: an inflammatory illness?
Next Document:  Viral Pneumonia in Adults.