| Update on the pathophysiology and management of idiopathic intracranial hypertension. | |
| | |
MedLine Citation:
|
PMID: 22423118 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Idiopathic intracranial hypertension is a disease of unknown aetiology, typically affecting young obese women, producing a syndrome of increased intracranial pressure without identifiable cause. Despite a large number of hypotheses and publications over the past decade, the aetiology is still unknown. Vitamin A metabolism, adipose tissue as an actively secreting endocrine tissue and cerebral venous abnormalities are areas of active study regarding the pathophysiology of idiopathic intracranial hypertension. There continues to be no evidence based consensus or formal guidelines regarding management and treatment of the disease. Treatment studies show that the diagnostic lumbar puncture is a valuable intervention beyond its diagnostic importance, and that weight management is critical. However, many questions remain regarding the efficacy of acetazolamide, CSF shunting procedures and cerebral transverse venous sinus stenting. |
| | |
Authors:
|
Valérie Biousse; Beau B Bruce; Nancy J Newman |
Related Documents
:
|
8149698 - Pulmonary vascular reactivity and ischaemia-reperfusion injury in the rat. 22784888 - Prevention and treatment of orthostatic hypotension in the orthopedic patient population. 3157028 - Protection of the hypertrophied pig myocardium. a comparison of crystalloid, blood, and... 8048858 - Effects of a novel 21-aminosteroid or methylprednisolone in experimental total intestin... 132688 - Regional lung perfusion and pulmonary artery pressure in chronic obstructive lung disease. 6349388 - Cardiovascular changes from expiration to inspiration during ippv. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2012-03-15 |
Journal Detail:
|
Title: Journal of neurology, neurosurgery, and psychiatry Volume: 83 ISSN: 1468-330X ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 2012 May |
Date Detail:
|
Created Date: 2012-04-11 Completed Date: 2012-06-12 Revised Date: 2013-05-20 |
Medline Journal Info:
|
Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: England |
Other Details:
|
Languages: eng Pagination: 488-94 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, Emory University, Atlanta, GA, USA. vbiouss@emory.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bariatric Surgery
/
statistics & numerical data Carbonic Anhydrase Inhibitors / therapeutic use Humans Magnetic Resonance Imaging Obesity / complications*, surgery Prevalence Pseudotumor Cerebri* / complications, drug therapy, epidemiology, physiopathology, surgery |
| Grant Support | |
ID/Acronym/Agency:
|
K23 EY019341/EY/NEI NIH HHS; K23-EY019341/EY/NEI NIH HHS; KL2 RR025009/RR/NCRR NIH HHS; KL2-RR025009/RR/NCRR NIH HHS; P30 EY006360/EY/NEI NIH HHS; P30-EY06360/EY/NEI NIH HHS; UL1 RR025008/RR/NCRR NIH HHS; UL1-RR025008/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Carbonic Anhydrase Inhibitors |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Depression: an inflammatory illness?
Next Document: Viral Pneumonia in Adults.