Document Detail


Update on the pathophysiological basics of cardiac resynchronization therapy.
MedLine Citation:
PMID:  18482999     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cardiac resynchronization therapy is an established treatment for patients with severe heart failure and ventricular conduction disturbance. Cardiac resynchronization therapy improves cardiac pump function and clinical status, and reduces morbidity and mortality. This electrical treatment for heart failure has also contributed enormously to the understanding of the pathophysiology of ventricular conduction disturbance. This article highlights the latest findings about the pathophysiology of ventricular conduction disturbance and pacing as well as that of resynchronization, with emphasis on the role of regional mechanical performance in triggering remodeling processes involved and on the selection of patients using mechanical dyssynchrony.
Authors:
Angelo Auricchio; Frits W Prinzen
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-05-14
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  10     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-23     Completed Date:  2008-09-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  797-800     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Fondazione Cardiocentro Ticino, Via Tesserete 48, 6900 Lugano, Switzerland. angelo.auricchio@cardiocentro.org
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MeSH Terms
Descriptor/Qualifier:
Cardiac Pacing, Artificial*
Electrocardiography
Heart Conduction System / physiopathology
Heart Failure / physiopathology*,  therapy*
Humans
Pacemaker, Artificial
Prognosis

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