Document Detail

Update on montelukast and its role in the treatment of asthma, allergic rhinitis and exercise-induced bronchoconstriction.
MedLine Citation:
PMID:  17714069     Owner:  NLM     Status:  MEDLINE    
Montelukast sodium (Singulair, Merck and Co., Inc., Whitehouse Station, NJ) is a selective and orally-active leukotriene receptor antagonist with demonstrated effectiveness for treating allergic asthma and allergic rhinitis in adults and children as young as 12 months of age for allergic asthma and 6 months of age for allergic rhinitis. It was recently approved in the US for prevention of exercise-induced bronchoconstriction in patients who are > or = 15 years of age. This paper updates a prior review of the data on the clinical efficacy of montelukast published in this journal.
William Storms
Related Documents :
7582279 - Cytokines in bronchoalveolar lavage fluid of patients with nocturnal asthma.
23914839 - Hydrolyzed collagen intake increases bone mass of growing rats trained with running exe...
10934069 - Quality of dyspnea in bronchoconstriction differs from external resistive loads.
6783059 - A controlled trial of ketotifen in exercise-induced asthma.
15034069 - Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic as...
1750339 - Psychological and respiratory physiological effects of a physical exercise programme on...
20353489 - Mechanisms of exercise-induced improvements in the contractile apparatus of the mammali...
6949469 - Hydralazine in chronic chf.
9124329 - Tricarboxylic acid cycle intermediates in human muscle at rest and during prolonged cyc...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Expert opinion on pharmacotherapy     Volume:  8     ISSN:  1744-7666     ISO Abbreviation:  Expert Opin Pharmacother     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-23     Completed Date:  2007-09-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897346     Medline TA:  Expert Opin Pharmacother     Country:  England    
Other Details:
Languages:  eng     Pagination:  2173-87     Citation Subset:  IM    
The William Storms Allergy Clinic, Colorado Springs, CO 80907, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acetates / therapeutic use*
Anti-Asthmatic Agents / administration & dosage,  therapeutic use
Asthma / drug therapy*
Asthma, Exercise-Induced / drug therapy
Bronchoconstriction / drug effects*
Leukotriene Antagonists / administration & dosage,  therapeutic use
Quinolines / therapeutic use*
Rhinitis, Allergic, Perennial / drug therapy*
Rhinitis, Allergic, Seasonal / drug therapy*
Reg. No./Substance:
0/Acetates; 0/Anti-Asthmatic Agents; 0/Leukotriene Antagonists; 0/Quinolines; 158966-92-8/montelukast

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Simvastatin: present and future perspectives.
Next Document:  Lapatinib: a tyrosine kinase inhibitor with a clinical role in breast cancer.