Document Detail


Update on montelukast and its role in the treatment of asthma, allergic rhinitis and exercise-induced bronchoconstriction.
MedLine Citation:
PMID:  17714069     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Montelukast sodium (Singulair, Merck and Co., Inc., Whitehouse Station, NJ) is a selective and orally-active leukotriene receptor antagonist with demonstrated effectiveness for treating allergic asthma and allergic rhinitis in adults and children as young as 12 months of age for allergic asthma and 6 months of age for allergic rhinitis. It was recently approved in the US for prevention of exercise-induced bronchoconstriction in patients who are > or = 15 years of age. This paper updates a prior review of the data on the clinical efficacy of montelukast published in this journal.
Authors:
William Storms
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Expert opinion on pharmacotherapy     Volume:  8     ISSN:  1744-7666     ISO Abbreviation:  Expert Opin Pharmacother     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-23     Completed Date:  2007-09-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897346     Medline TA:  Expert Opin Pharmacother     Country:  England    
Other Details:
Languages:  eng     Pagination:  2173-87     Citation Subset:  IM    
Affiliation:
The William Storms Allergy Clinic, Colorado Springs, CO 80907, USA. sneezedoc@stormsallergy.com
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MeSH Terms
Descriptor/Qualifier:
Acetates / therapeutic use*
Animals
Anti-Asthmatic Agents / administration & dosage,  therapeutic use
Asthma / drug therapy*
Asthma, Exercise-Induced / drug therapy
Bronchoconstriction / drug effects*
Humans
Leukotriene Antagonists / administration & dosage,  therapeutic use
Quinolines / therapeutic use*
Rhinitis, Allergic, Perennial / drug therapy*
Rhinitis, Allergic, Seasonal / drug therapy*
Chemical
Reg. No./Substance:
0/Acetates; 0/Anti-Asthmatic Agents; 0/Leukotriene Antagonists; 0/Quinolines; 158966-92-8/montelukast

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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