| Update on the concept of the cell cycle: the contribution of flow cytometry. | |
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MedLine Citation:
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PMID: 2435348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Flow cytometry has been extensively used to provide accurate estimates of the relative amounts of various cellular constituents (DNA, RNA, proteins) for cell kinetic studies. Multiparametric analysis also supports the recent concept that cell growth and the DNA division cycle may be under distinct regulatory mechanisms. Moreover, metabolic subcompartments of the cell cycle, distinguished by flow cytometry, have offered a highly sensitive cell classification in comparison with the conventional distinction of the four main phases of the cell cycle. Finally, a new sensitive and powerful technology, BrdU/DNA analysis, represents a remarkable maturing of a very useful alternative for the study of DNA synthesis and cell cycle traverse. |
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Authors:
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X Ronot; M Adolphe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biology of the cell / under the auspices of the European Cell Biology Organization Volume: 58 ISSN: 0248-4900 ISO Abbreviation: Biol. Cell Publication Date: 1986 |
Date Detail:
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Created Date: 1987-05-18 Completed Date: 1987-05-18 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8108529 Medline TA: Biol Cell Country: FRANCE |
Other Details:
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Languages: eng Pagination: 113-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Cycle* Cell Differentiation Cell Division DNA / analysis Flow Cytometry / methods Kinetics Mitosis RNA / analysis |
| Chemical | |
Reg. No./Substance:
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63231-63-0/RNA; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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