Document Detail

Update on antidotes for pediatric poisoning.
MedLine Citation:
PMID:  17110870     Owner:  NLM     Status:  MEDLINE    
Antidotes are playing an increasing role in therapy for pediatric poisonings. Although initial response to all pediatric poisonings begins with basic stabilization, knowledge of specific antidotes, their mechanisms of action, safety profile in pediatrics, and dosing regimens can be life-saving for pediatric victims of nerve gas exposure, acetaminophen toxicity, methanol and ethylene glycol ingestion, and snakebites. This article presents an overview of the pathophysiology, symptoms, antidotes, and emergency management of these toxicological emergencies.
Marjorie Lee White; Erica L Liebelt
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric emergency care     Volume:  22     ISSN:  1535-1815     ISO Abbreviation:  Pediatr Emerg Care     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-11-19     Completed Date:  2006-12-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8507560     Medline TA:  Pediatr Emerg Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  740-6; quiz 747-9     Citation Subset:  IM    
Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
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MeSH Terms
Acetaminophen / poisoning
Acetylcysteine / administration & dosage,  therapeutic use
Administration, Oral
Antidotes / therapeutic use*
Antivenins / administration & dosage,  therapeutic use
Child, Preschool
Cholinergic Antagonists / administration & dosage,  therapeutic use
Cholinesterase Inhibitors / poisoning
Crotalid Venoms / poisoning
Ethylene Glycol / poisoning
Immunoglobulin Fragments / administration & dosage,  therapeutic use
Infusions, Intravenous
Injections, Intramuscular / instrumentation
Methanol / poisoning
Poisoning / diagnosis,  drug therapy*
Practice Guidelines as Topic
Pyrazoles / administration & dosage,  therapeutic use
Snake Bites / drug therapy
Reg. No./Substance:
0/Antidotes; 0/Antivenins; 0/Cholinergic Antagonists; 0/Cholinesterase Inhibitors; 0/Crotalid Venoms; 0/Crotalidae Polyvalent immune Fab; 0/Immunoglobulin Fragments; 0/Pyrazoles; 103-90-2/Acetaminophen; 107-21-1/Ethylene Glycol; 616-91-1/Acetylcysteine; 67-56-1/Methanol; 7554-65-6/fomepizole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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