| Update on medications with adverse skeletal effects. | |
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MedLine Citation:
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PMID: 21389249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients rely on their primary care physician to manage multiple, often chronic medical conditions that require prescription medications. Balancing the risk to benefit of treatments can be challenging and requires that the primary care physician stay abreast of new information regarding risks and benefits. The number of medications with reported adverse effects on skeletal health is expanding. This review focuses on medications recently added to the list of "bad to the bone" drugs and on recent advances in management of glucocorticoid-induced osteoporosis. A practical approach to assessing and managing the skeletal risks is outlined. |
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Authors:
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Caroline J Davidge Pitts; Ann E Kearns |
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Publication Detail:
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Type: Journal Article; Review Date: 2011-03-09 |
Journal Detail:
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Title: Mayo Clinic proceedings. Mayo Clinic Volume: 86 ISSN: 1942-5546 ISO Abbreviation: Mayo Clin. Proc. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-01 Completed Date: 2011-06-23 Revised Date: 2012-05-07 |
Medline Journal Info:
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Nlm Unique ID: 0405543 Medline TA: Mayo Clin Proc Country: United States |
Other Details:
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Languages: eng Pagination: 338-43; quiz 343 Citation Subset: AIM; IM |
Affiliation:
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Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aromatase Inhibitors / adverse effects, therapeutic use Bone Density / drug effects Bone and Bones / drug effects* Breast Neoplasms / drug therapy Contraceptive Agents, Female / adverse effects Diphosphonates / therapeutic use Fractures, Bone / chemically induced Glucocorticoids / adverse effects Gonadotropin-Releasing Hormone / agonists Humans Medroxyprogesterone Acetate / adverse effects Osteoporosis / chemically induced*, drug therapy Peroxisome Proliferator-Activated Receptors / agonists Proton Pump Inhibitors / therapeutic use Serotonin Uptake Inhibitors / adverse effects, therapeutic use Thiazolidinediones / adverse effects, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Aromatase Inhibitors; 0/Contraceptive Agents, Female; 0/Diphosphonates; 0/Glucocorticoids; 0/Peroxisome Proliferator-Activated Receptors; 0/Proton Pump Inhibitors; 0/Serotonin Uptake Inhibitors; 0/Thiazolidinediones; 33515-09-2/Gonadotropin-Releasing Hormone; 71-58-9/Medroxyprogesterone Acetate |
| Comments/Corrections | |
Comment In:
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Mayo Clin Proc. 2011 Sep;86(9):916
[PMID:
21878606
]
Mayo Clin Proc. 2011 Sep;86(9):916-7; author reply 917 [PMID: 21878605 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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