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Update on the mechanisms of gastric acid secretion.
MedLine Citation:
PMID:  20821079     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Acid-related disorders represent a major healthcare concern. In recent years, our understanding of the physiologic processes underlying gastric acid secretion has improved notably. The identity of several apical ion transport proteins, which are necessary for acid secretion to take place, has been resolved. The recent developments have uncovered potential therapeutic targets for the treatment of acid-related disorders. This brief review provides an update on the mechanisms of gastric acid secretion, with a particular focus on apical ion transport.
Authors:
Sascha Kopic; John P Geibel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current gastroenterology reports     Volume:  12     ISSN:  1534-312X     ISO Abbreviation:  Curr Gastroenterol Rep     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888896     Medline TA:  Curr Gastroenterol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  458-64     Citation Subset:  IM    
Affiliation:
Departments of Surgery and Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.
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