| An update on the evaluation and management of pulmonary hypertension in scleroderma. | |
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MedLine Citation:
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PMID: 22215445 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pulmonary arterial hypertension associated with scleroderma (SScPAH) is a debilitating, highly lethal condition that responds to an array of therapies. Quality of life and prognosis are substantially improved by treatment, and early diagnosis and treatment are associated with improved outcomes. There are serious limitations to current screening programs. Many more questions need to be addressed. Why is PAH so common in SSc? Why is the tolerance of pulmonary hypertension so poor in scleroderma? What are the best measures of response to therapy in SSc patients with PAH? Should we use different parameters in prognostic scores in SScPAH? Why is postcapillary pulmonary hypertension so common in SSc? How do we reliably differentiate lung disease-associated pulmonary hypertension from PAH? The aim of this review is to summarize the main areas of progress over the past decade and to look to the challenges for the next decade. |
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Authors:
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John G Coghlan; Benjamin Schreiber; Benjamin Schrieber |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current rheumatology reports Volume: 14 ISSN: 1534-6307 ISO Abbreviation: Curr Rheumatol Rep Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-01-10 Completed Date: 2012-05-08 Revised Date: 2012-06-11 |
Medline Journal Info:
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Nlm Unique ID: 100888970 Medline TA: Curr Rheumatol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 1-10 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Royal Free Hospital, London NW3 2QG, England, UK. gerry.coghlan@nhs.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Hypertension, Pulmonary* / diagnosis, drug therapy, etiology Scleroderma, Systemic / complications* |
| Comments/Corrections | |
Erratum In:
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Curr Rheumatol Rep. 2012 Jun;14(3):294 Note: Schrieber, Benjamin [corrected to Schreiber, Benjamin] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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