Document Detail


Update on anticonvulsant drugs.
MedLine Citation:
PMID:  20490745     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 2009, the US Food and Drug Administration approved three medications for the treatment of epilepsy: rufinamide, lacosamide, and vigabatrin. In addition, extended-release formulations of lamotrigine and levetiracetam were approved recently. When added to the dozen medications for treating epilepsy, the choice is a luxury in terms of additional options, but also a challenge for practitioners to use them all with expertise. Recently, there has been much interest surrounding medications for epilepsy and their possible association with osteoporosis, safety during pregnancy, biological equivalence to generic versions, and possible association with higher rates of suicidality. This review discusses these issues and provides a current overview for the medical management of epilepsy.
Authors:
Derek J Chong; Carl W Bazil
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current neurology and neuroscience reports     Volume:  10     ISSN:  1534-6293     ISO Abbreviation:  Curr Neurol Neurosci Rep     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-05-27     Completed Date:  2010-08-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100931790     Medline TA:  Curr Neurol Neurosci Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  308-18     Citation Subset:  IM    
Affiliation:
Columbia Comprehensive Epilepsy Center, Department of Neurology, Columbia University, 710 West 168th Street, 7th Floor, New York, NY 10032, USA. dc2223@mail.cumc.columbia.edu
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Drug-Induced
Anticonvulsants / adverse effects,  pharmacology,  therapeutic use*
Body Weight / drug effects
Drug Approval
Epilepsy / drug therapy*
Female
Humans
Pregnancy
Pregnancy Complications / chemically induced
Chemical
Reg. No./Substance:
0/Anticonvulsants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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