Document Detail


Upconverting luminescent nanoparticles for use in bioconjugation and bioimaging.
MedLine Citation:
PMID:  20829098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Upconverting luminescent nanoparticles (UCNPs) display the unique property of emitting visible light following photoexcitation with near-infrared laser light. This results in features such as virtually zero autofluorescence of (biological) matter and easy separation of the emission peaks from stray light. Other features include rather narrow emission bands, very high chemical stability, the lack of bleaching, and the absence of blinking effects. This article reviews the work performed in the past few years with UCNPs in terms of surface modifications, bioconjugation, and optical (cellular) imaging.
Authors:
Heike S Mader; Peter Kele; Sayed M Saleh; Otto S Wolfbeis
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-09-07
Journal Detail:
Title:  Current opinion in chemical biology     Volume:  14     ISSN:  1879-0402     ISO Abbreviation:  Curr Opin Chem Biol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-12     Completed Date:  2011-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9811312     Medline TA:  Curr Opin Chem Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  582-96     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, 93040 Regensburg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Animals
Humans
Light*
Luminescent Agents / chemical synthesis,  chemistry*
Molecular Imaging / methods*
Nanoparticles / chemistry*
Surface Properties
Chemical
Reg. No./Substance:
0/Luminescent Agents

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