| Up-expression of GAD65 in the amygdala of the rat model of choric immobilization stress with elevated blood glucose. | |
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MedLine Citation:
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PMID: 21907636 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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It is considered that hypothalamus is important in the regulation of the blood glucose, but how chronic stress leads to hyperglycemia is not known. In this experiment, we used chronic immobilization stress rat as a model, and observed that only rats with increased expression of GAD65 in the amygdala had an elevated level of blood glucose. Considering there are fiber tracks between the amygdala and hypothalamus, some of which are GABAergic, this result may indicate that the change of GAD65 expression in the amygdala may be related to changes in blood glucose levels. Therefore, the amygdala may be involved in the hyperglycemic response to stress. |
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Authors:
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Xiao-Jing Li; Wei Zhang; Bing Liang; Xiang Zheng; Xue Zhou |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-8 |
Journal Detail:
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Title: Autonomic neuroscience : basic & clinical Volume: - ISSN: 1872-7484 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100909359 Medline TA: Auton Neurosci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Histology, Embryology and Neurobiology, West China School of Preclinical Medicine and Forensic Medicine, Sichuan University, Chengdu, Sichuan Province, P. R. China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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