Document Detail


Unusual site thrombosis.
MedLine Citation:
PMID:  22000092     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Venous thromboses in unusual sites are rare and heterogenous manifestations of venous thromboembolism (VTE). These uncommon diseases are each characterized by peculiar pathophysiological and clinical features, mainly reflecting the different characteristics of the organs of origin. Moreover, the relative frequency and importance of risk factors associated with their development may be different compared to those of the classical manifestations of VTE, such as deep vein thrombosis of the lower limbs or pulmonary embolism. The need for anticoagulant therapy for unusual site thrombosis (UST) is generally accepted. However, several questions remain unanswered: what is the best therapeutic agent, is it safe, and for how long should it be used? These questions persist mainly due to the low level of available evidence given the rarity of these diseases. The short- and long-term prognoses, and in particular the risk of recurrence and mortality, are quite heterogenous among the different manifestations of UST and even within each of them, depending mainly on the predisposing causes.
Authors:
Marco P Donadini; Walter Ageno
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in hematology     Volume:  48     ISSN:  1532-8686     ISO Abbreviation:  Semin. Hematol.     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404514     Medline TA:  Semin Hematol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  264-70     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Thrombosis Center, Division of Internal Medicine 1, Circolo Hospital-University of Insubria, Varese, Italy.
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