| Unusual presentation of a case of Sjogren's syndrome with neurological and ocular manifestation. | |
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MedLine Citation:
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PMID: 22098691 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Sjogren's syndrome is an autoimmune disease that commonly presents to the ophthalmologist as a dry eye disease. We report an unusual presentation of a case of Sjogren's syndrome. A 33-year-old man presented with lid swelling, pseudomembraneous conjunctivitis with central corneal epithelial defect and history of limb weakness for past 2 years. There was progressive enlargement of the epithelial defect and conjunctival-scleral necrosis developed during follow-up. Evaluation for underlying connective tissue disorder was positive for SS-B/La antibody and, the rheumatoid factor, anti nuclear antibody, anti neutrophil cytoplasmic antibody titres were negative. Patient was diagnosed as a case of Primary Sjogren's syndrome. Resolution of the conjunctival-scleral necrosis occurred following treatment with combination of cyclosporine and prednisolone. Paramedian tarsorrhaphy was performed to promote healing of the corneal epithelium. The corneal epithelium healed, conjunctival-scleral necrosis resolved completely and the visual acuity improved to 6/36 in the right eye after 3 months of immunosuppressive therapy. The immunosuppressive therapy was discontinued after completion of 6 months of treatment. After 6 months follow-up of stopping immunosuppressive therapy, the ocular and systemic condition is stable. |
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Authors:
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Naina R Bamrolia; Ritu Arora; Usha Yadava |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-16 |
Journal Detail:
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Title: Contact lens & anterior eye : the journal of the British Contact Lens Association Volume: - ISSN: 1476-5411 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9712714 Medline TA: Cont Lens Anterior Eye Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi 110002, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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