Document Detail

Unusual megaloblastic anaemia wiht multinucleate erythroblasts: two cases with septicaemia and acute renal failure.
MedLine Citation:
PMID:  1127125     Owner:  NLM     Status:  MEDLINE    
The case histories and blood pictures of two patients who had cardiac lesions, septicaemia, and renal failure and terminally developed a leucoerythroblastic anaemia with megloblastic features associated with multinucleate erythroblasts, are described. Though folate deficiency may have made a minor contribution to the blood abnormalities, it is considered that some other disturbance in erythropoiesis was responsible for the bizarre blood and bone marrow changes in these patients. Similar cases reported in the earlier literature are reviewed.
M Saary; J G Sissons; W A Davies; A V Hoffbrand
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  28     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-08-07     Completed Date:  1975-08-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  324-31     Citation Subset:  AIM; IM    
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MeSH Terms
Anemia, Macrocytic / blood*
Anemia, Megaloblastic / blood*,  complications,  etiology
Blood Cell Count
Bone Marrow Cells
Cell Nucleus
Erythrocytes, Abnormal*
Folic Acid Deficiency / complications
Kidney Failure, Acute / complications*
Middle Aged
Sepsis / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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