Document Detail


Unusual histological findings in a child with idiopathic nephrotic syndrome.
MedLine Citation:
PMID:  17077973     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a 2-year-old child with corticosteroid-resistant nephrotic syndrome whose renal biopsy revealed light microscopically normal glomeruli but highly unusual finger-like projections and arches of the glomerular basement membrane. To our knowledge, the association between nephrotic syndrome and this patient's rare ultrastuctural lesion has not been previously documented in the literature. It is not certain whether this basement membrane is pathogenic or a striking but coincidental developmental anomaly.
Authors:
James Springate; Tibor Nadasdy
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-11-01
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  22     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-02-05     Completed Date:  2007-07-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  451-3     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, School of Medicine and Biomedical Sciences, State University of New York, and Division of Nephrology, Women and Children's Hospital, Buffalo, NY, 14214, USA. jspringate@upa.chob.edu
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Female
Glomerular Basement Membrane / pathology,  ultrastructure*
Humans
Kidney Glomerulus / pathology*
Nephrotic Syndrome / pathology*

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