Document Detail

Unusual findings on cystoscopy in a patient with detrusor overactivity.
MedLine Citation:
PMID:  22543775     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Chronic lithium ingestion has been shown to cause polyuria and polydipsia in 20% to 40% of patients, secondary to diabetes insipidus. However, it has not been reported to cause lithium deposition in the bladder.
CASE: A 77-year-old woman presented to our clinic with complaints of urinary incontinence, urinary urgency, and nocturnal enuresis for the past 3 to 4 years. She denied polydipsia. Her medical history was significant for bipolar disorder for which she had been on lithium therapy for more than 10 years. Metallic deposition was noted in the suburothelium of a urethral biopsy by gross inspection.
CONCLUSION: Suburothelial deposition of metal may act as a bladder irritant and account for this patient's overactive bladder symptoms.
Patrick A Nosti; Andrew I Sokol
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Female pelvic medicine & reconstructive surgery     Volume:  18     ISSN:  2151-8378     ISO Abbreviation:  Female Pelvic Med Reconstr Surg     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101528690     Medline TA:  Female Pelvic Med Reconstr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  186-7     Citation Subset:  IM    
Section of Female Pelvic Medicine and Reconstructive Surgery, Department of Women and Infants' Services, Washington Hospital Center, Georgetown University School of Medicine, Washington, DC.
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