Document Detail


Unusual extramedullary hematopoiesis in a patient receiving granulocyte colony-stimulating factor.
MedLine Citation:
PMID:  17016039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 42-year-old woman was diagnosed with myelodysplastic syndrome with fibrosis that developed bilaterally, cervical lymphadenopathy and cutaneous infiltration by trilineage extramedullary hematopoiesis after granulocyte colony-stimulating factor therapy because of severe neutropenia. Hepatosplenomegaly was not observed during her follow-up. Extramedullary hematopoiesis disappeared after growth factor therapy was stopped. Although the neutropenia was alleviated by growth factor administration, the appearance of an unusual involvement of extramedullary hematopoiesis should be kept in mind.
Authors:
Simten Dagdas; Gulsum Ozet; Guchan Alanoglu; Meltem Ayli; Ayla Gokmen Akoz; Selim Erekul
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta haematologica     Volume:  116     ISSN:  0001-5792     ISO Abbreviation:  Acta Haematol.     Publication Date:  2006  
Date Detail:
Created Date:  2006-10-03     Completed Date:  2006-10-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0141053     Medline TA:  Acta Haematol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  198-202     Citation Subset:  IM    
Copyright Information:
Copyright 2006 S. Karger AG, Basel.
Affiliation:
Department of Hematology, Ankara Numune Hospital, Ankara, Turkey. simtendagdas@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Face / pathology
Female
Fibrosis / drug therapy*
Granulocyte Colony-Stimulating Factor / adverse effects*
Hematopoiesis, Extramedullary / drug effects*
Humans
Myelodysplastic Syndromes / drug therapy*
Chemical
Reg. No./Substance:
143011-72-7/Granulocyte Colony-Stimulating Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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