Document Detail


Unusual electrocardiographic changes with propranolol and diltiazem overdosage: a case report.
MedLine Citation:
PMID:  12845395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The therapeutic efficacy and safety of beta-adrenoreceptor-blocking drugs has been well established in patients with angina pectoris, cardiac arrhythmias, and hypertension and reducing the risk of mortality and nonfatal reinfarction on survival of acute myocardial infarction. The calcium antagonists are used for the treatment of patients with angina pectoris, long-term systemic hypertension, and the management of hypertensive emergencies and also for a multitude of other cardiovascular and noncardiovascular conditions. Because adverse cardiovascular effects can occur, however, patients being considered for combination treatment with propranolol and diltiazem must be selected carefully and observed closely. In this article, we present a suicidal case of drug overdose with propranolol and diltiazem with unusual electrocardiographic changes.
Authors:
Salim Satar; Ayca Acikalin; Onur Akpinar
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of therapeutics     Volume:  10     ISSN:  1075-2765     ISO Abbreviation:  Am J Ther     Publication Date:    2003 Jul-Aug
Date Detail:
Created Date:  2003-07-07     Completed Date:  2003-11-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9441347     Medline TA:  Am J Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  299-302     Citation Subset:  IM    
Affiliation:
Emergency Department, Faculty of Medicine, Cukurova University, Adana, Turkey. ssatar@mail.cu.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adrenergic beta-Antagonists / poisoning*
Calcium Channel Blockers / poisoning*
Diltiazem / poisoning*
Drug Interactions
Electrocardiography / drug effects*
Female
Humans
Overdose
Propranolol / poisoning*
Suicide, Attempted*
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Calcium Channel Blockers; 42399-41-7/Diltiazem; 525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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