Document Detail

Unusual deficiency of the modified purine base queuine in transfer ribonucleic acid from the human placenta as tested by enzymatic assay.
MedLine Citation:
PMID:  8372867     Owner:  NLM     Status:  MEDLINE    
Transfer ribonucleic acid from rapidly growing tissues, particularly from neoplasia, is partially deficient in queuine, a highly modified transfer ribonucleic acid constituent. By means of an enzymatic assay we also found a queuine deficiency (14%) in human placenta transfer ribonucleic acid despite its high concentrations in the amniotic fluid. Proposed cause and significance of the results are discussed.
W Baranowski; J Tomaszewski; G Keith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  169     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-10-14     Completed Date:  1993-10-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  581-2     Citation Subset:  AIM; IM    
Second Clinic of Gynecological Surgery, Academy of Medicine, Lublin, Poland.
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MeSH Terms
Guanine / analogs & derivatives*,  chemistry
Placenta / chemistry*
RNA, Transfer / chemistry*
Reg. No./Substance:
72496-59-4/queuine; 73-40-5/Guanine; 9014-25-9/RNA, Transfer

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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