Document Detail


Unusual cause of seizure.
MedLine Citation:
PMID:  8858658     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: This case report of camphor ingestion in a 15-month-old child illustrates the potential toxicity of a common household product. Details of the patient presentation are reported along with a review of the literature. METHODS: Patient information was collected using the records of Poison Control, the Emergency Department, and the Health Records at the Hospital for Sick Children in Toronto, Ontario, Canada. A comprehensive review of the literature was conducted using the MEDLINE database for the time period 1966 to April 1995. DISCUSSION: Oral ingestion of camphor is unusual, given that these products have both unpleasant taste and texture. This patient ingested 70 ml of an over-the-counter medicated ointment containing 4.73% camphor, 2.6% menthol, and 1.2% eucalyptus oil. While the concentration of camphor in this product is low, an estimated 280 mg/kg of camphor was consumed. With significant ingestion of camphor (> 50 mg/kg), neurologic toxicity is common. In this patient, prolonged generalized tonic-clonic seizure activity was noted approximately two hours post single acute ingestion of camphor. This delay in onset of seizure activity is atypical, as seizures have previously been noted to occur in the 90 minutes following ingestion. CONCLUSION: Readily available medicated ointments containing camphor have potential for serious or fatal consequences when ingested by children.
Authors:
S Gouin; H Patel
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric emergency care     Volume:  12     ISSN:  0749-5161     ISO Abbreviation:  Pediatr Emerg Care     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-12-06     Completed Date:  1996-12-06     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8507560     Medline TA:  Pediatr Emerg Care     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  298-300     Citation Subset:  IM    
Affiliation:
Division of Emergency Medicine, Hospital for Sick Children, University of Toronto, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Anti-Infective Agents, Local / poisoning*
Camphor / poisoning*
Female
Humans
Infant
Nonprescription Drugs / poisoning
Ointments
Poisoning / therapy
Status Epilepticus / chemically induced*
Chemical
Reg. No./Substance:
0/Anti-Infective Agents, Local; 0/Nonprescription Drugs; 0/Ointments; 76-22-2/Camphor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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