Document Detail

Unusual cardiovascular manifestations of sarcoidosis, a report of three cases: coronary artery aneurysm with myocardial infarction, symptomatic mitral valvular disease, and sudden death from ruptured splenic artery.
MedLine Citation:
PMID:  19502084     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Cardiac and vascular involvement by sarcoid is only rarely recognized clinically. Involvement of muscular arteries such as epicardial coronaries or the splenic artery has not been previously reported in these patients, and valvular disease has been reported only rarely. METHODS: We present herein clinical, imaging and pathologic documentation of three such patients, each displaying one of these unusual manifestations and enlarging the spectrum of cardiac sarcoid. RESULTS: The presentations were life threatening, one with myocardial infarction caused by a coronary artery aneurysm, a second with splenic artery rupture and hemorrhage, and the third with severe mitral regurgitation. The clinical and histopathologic findings are described and a review of the literature is undertaken.
Joel H Barton; Fabio Tavora; Andrew Farb; Ling Li; Allen P Burke
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-06-06
Journal Detail:
Title:  Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology     Volume:  19     ISSN:  1879-1336     ISO Abbreviation:  Cardiovasc. Pathol.     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-10-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9212060     Medline TA:  Cardiovasc Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e119-23     Citation Subset:  IM    
Armed Forces Institute of Pathology, Washington, DC, USA.
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MeSH Terms
Aneurysm, Ruptured / complications,  pathology*
Coronary Aneurysm / complications,  pathology*
Coronary Vessels / pathology
Death, Sudden
Fatal Outcome
Hemorrhage / etiology,  pathology
Middle Aged
Mitral Valve Insufficiency / complications,  pathology*
Myocardial Infarction / etiology,  pathology*
Sarcoidosis / complications,  pathology*
Splenic Artery / pathology
Splenic Rupture / complications,  pathology*

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