Document Detail


Unusual cardiovascular localization of nonamyloid immunoglobulin deposition disease causing sudden death.
MedLine Citation:
PMID:  1542638     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case of a 38-yr-old man is presented in whom sudden death was attributed to coronary ostial stenosis caused by aortic intimal deposits of an amyloid-like material. Autopsy revealed wide-spread lymphocytic lymphoma with kappa light chain restriction. Histochemistry, immunoperoxidase light microscopy, transmission electron microscopy, and immunoelectron microscopy identified the coronary ostial, and massive other cardiovascular, deposits as para-amyloid of kappa light chain origin.
Authors:
V M Walley; M M Silver
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc     Volume:  5     ISSN:  0893-3952     ISO Abbreviation:  Mod. Pathol.     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-04-09     Completed Date:  1992-04-09     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8806605     Medline TA:  Mod Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  89-93     Citation Subset:  IM    
Affiliation:
University of Ottawa Heart Institute, Department of Anatomical Pathology, Ottawa Civic Hospital, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aorta / chemistry,  metabolism,  ultrastructure
Aortic Valve Stenosis / complications,  metabolism
Cardiovascular System / chemistry*,  metabolism,  ultrastructure
Death, Sudden / etiology*
Humans
Immunoglobulin kappa-Chains / analysis*,  metabolism
Immunohistochemistry / methods
Male
Microscopy, Electron
Microscopy, Immunoelectron
Chemical
Reg. No./Substance:
0/Immunoglobulin kappa-Chains

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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