Document Detail


Unusual aspect of Pernicious Anemia during association of Beta-Thalassemia: a new case report and literature review.
MedLine Citation:
PMID:  22766185     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Pernicious anemia appears classically by macrocytosis. We report a case of a late discovered Biermer disease, on a 42-year-old young black woman. The reason was an unusual aspect of this disease in a context of betathalassemia. The patient presented chronic anemia which evolved during about ten year. Biology showed a normocytosis and signs of hemolysis according to beta-thalassemia. This was confirmed by an electrophoresis showing 9.1 % of fraction F some haemoglobin. Since this date, the patient was treated by folic acid alone with periodic transfusions of red blood cell. She presented eight years after the beginning of her disease, neurological deterioration. Diagnosis of pernicious anemia was finally established up on histological gastritis, low level of the blood rate of vitamin B12, macrocytosis, and presence of intrinsic anti-factor and parietal anti-cells antibodies.
Authors:
Madoky Magatte Diop; Ps Toure; My Leye; A Leye; S El Fadjri; M Diop; Mm Ka; Oulimata D Diop; S Fall; Fs Ndiaye
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Le Mali medical     Volume:  27     ISSN:  1993-0836     ISO Abbreviation:  -     Publication Date:  2012  
Date Detail:
Created Date:  2012-7-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  18420390R     Medline TA:  Mali Med     Country:  -    
Other Details:
Languages:  ENG; FRE     Pagination:  71-72     Citation Subset:  -    
Vernacular Title:
Maladie De Biermer De Presentation Inhabituelle Sur Un Profil Beta Thalassemique : Apport D'Un Nouveau Cas Et Revue De La Litterature.
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