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Unusual Features of Gastrointestinal Stromal Tumor on PET/CT and CT Imaging.
MedLine Citation:
PMID:  21285671     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. It can be benign or malignant in behavior. Stomach, being the most common site (70%) for GISTs, is followed by the small intestine (20%). Anorectal, colonic, and esophageal GISTs are uncommon, whereas extraintestinal GISTs are extremely rare. The presenting symptoms are highly dependent on tumor size and location, although a large number of GISTs are asymptomatic. The purpose of this article is to highlight the unusual characteristics of GISTs illustrated by PET/CT and CT imaging. These characteristics are organized into (1) unusual tumor location, (2) unusual clinical presentation, and (3) unusual sites of metastasis. Knowing the uncommon features of GISTs is important, as they are more often seen nowadays with the increasingly important role of PET/CT and CT in GIST management; and these tumors are associated with a poorer prognosis and unwanted delay in diagnosis is avoidable. With the availability of effective treatment by imatinib mesylate, a prompt and early diagnosis is essential for disease control. All GISTs illustrated in this article are pathologically proven.
Authors:
Chun-Sing Wong; Yiu-Ching Tiffany Chu; Pek-Lan Khong
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  36     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e1-7     Citation Subset:  IM    
Affiliation:
From the *Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, People's Republic of China, China; and †Department of Radiology, Kwong Wah Hospital, Hong Kong, People's Republic of China.
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