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An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report.
MedLine Citation:
PMID:  22229036     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
We report a 33-year-old Malay woman presented with acute left dense hemiparesis and an NIHSS score of 11/15. Computed tomography (CT) scan brain showed a massive right middle cerebral artery (MCA) territory infarct. The right internal carotid artery (ICA) and right proximal MCA were shown occluded from digital substraction angiography (DSA). Carotid dissection, carotid canal anomaly, and intercavernous communication were systematically ruled out. She had no risk factors for atherosclerosis. The connective tissue screening and thrombophilic markers were negative. However, she was anaemic on admission and subsequent investigations revealed that she had alpha-thalassemia and iron deficiency anaemia. The right ICA remained occluded from a repeat CT cerebral angiogram after one year, but otherwise she was neurologically stable. This case illustrates an unusual association between intracranial vessel occlusion with iron deficiency anaemia and alpha-thalassemia trait.
Authors:
Yeong Yeh Lee; Shalini Bhaskar
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Publication Detail:
Type:  Journal Article     Date:  2011-12-20
Journal Detail:
Title:  Case reports in medicine     Volume:  2011     ISSN:  1687-9635     ISO Abbreviation:  Case Rep Med     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-09     Completed Date:  2012-08-23     Revised Date:  2013-02-21    
Medline Journal Info:
Nlm Unique ID:  101512910     Medline TA:  Case Rep Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  271560     Citation Subset:  -    
Affiliation:
Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, 16150 Kota Bharu, Malaysia.
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