Document Detail

Unsuspected periventricular leukomalacia in children with strabismus: a case series.
MedLine Citation:
PMID:  17376186     Owner:  NLM     Status:  MEDLINE    
PURPOSE: We report a case series of seven patients who presented with strabismus and no apparent known neurological deficit. METHODS: A retrospective review of notes was performed on all patients presenting at the Royal Liverpool Children's Hospital (Alder Hey) with strabismus, in whom subsequent investigation revealed the presence of periventricular leukomalacia (PVL). RESULTS: All seven patients presented with esotropia. One patient also had dissociated vertical deviation. A history of premature birth was elicited in six cases; however, one patient had been born at 42 weeks. Apparently uncomplicated routine surgery produced unexpectedly poor results. CONCLUSIONS: Patients with undiagnosed PVL may present to the ophthalmologist with strabismus and no other apparent neurological abnormality. Where it is suspected that the patient may have suffered a significant hypoxic-ischaemic event, the ophthalmologist should have a low threshold for investigating with magnetic resonance imaging, particularly if the patient shows unexpected outcomes following appropriate treatment. Patients and parents should be counselled on possible suboptimal results prior to the offer of surgical correction of strabismus.
Wisam J Muen; Muhammad U Saeed; Musa Kaleem; Laurence Abernethy; Arvind Chandna
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-03-22
Journal Detail:
Title:  Acta ophthalmologica Scandinavica     Volume:  85     ISSN:  1395-3907     ISO Abbreviation:  Acta Ophthalmol Scand     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-27     Completed Date:  2007-10-23     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  9507578     Medline TA:  Acta Ophthalmol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  677-80     Citation Subset:  IM    
Department of Paediatric Ophthalmology, Royal Liverpool Children's Hospital (Alder Hey), Liverpool, UK.
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MeSH Terms
Brain / pathology
Child, Preschool
Esotropia / complications*,  diagnosis
Infant, Newborn
Infant, Premature
Leukomalacia, Periventricular / complications*,  diagnosis
Magnetic Resonance Imaging
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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