Document Detail

Unsuspected lupin allergens hidden in food.
MedLine Citation:
PMID:  16804325     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Lupin is a herbaceous plant from the legume family whose seed allergens usually have cross-reaction with peanut. Lupin flour is used in human nutrition because of its high nutritional and functional qualities. AIMS: The aim of this work was to detect non-specified lupin proteins contained in several manufactured foods. METHODS: Serum from a patient suffering anaphylactic episodes after ingestion of a certain brand of cookies and with oral allergy syndrome after eating chicken bouillon was used as a tracer. Lupin seeds and commercial food extracts were analyzed by SDS-PAGE, immunoblotting and immunoblotting inhibition. Lupin extract allergenicity after thermal processing was also analyzed. RESULTS: A lupin allergen with a molecular weight close to 14 kDa was detected in extracts from cookies, a chicken bouillon cube and a chicken dehydrated soup. CONCLUSIONS: The presence of unsuspected, hidden non-specified lupin sources in food labeling was demonstrated. According to the results of this study, it is important for food-allergic patients that food labels should declare all the components irrespective of their quantity.
B Rojas-Hijazo; M M Garcés; M L Caballero; P Alloza; I Moneo
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Publication Detail:
Type:  Journal Article     Date:  2006-06-27
Journal Detail:
Title:  International archives of allergy and immunology     Volume:  141     ISSN:  1018-2438     ISO Abbreviation:  Int. Arch. Allergy Immunol.     Publication Date:  2006  
Date Detail:
Created Date:  2006-08-16     Completed Date:  2006-09-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9211652     Medline TA:  Int Arch Allergy Immunol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  47-50     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2006 S. Karger AG, Basel.
Servicio Alergología, Hospital Clinico Universitario, Zaragoza, Spain.
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MeSH Terms
Allergens / analysis*,  immunology
Electrophoresis, Polyacrylamide Gel
Food Analysis
Food Hypersensitivity / etiology*
Food Labeling
Hot Temperature
Lupinus / adverse effects,  chemistry,  immunology*
Plant Extracts / immunology*
Seeds / chemistry
Reg. No./Substance:
0/Allergens; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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