Document Detail

Unsuccessful methotrexate treatment of a tubal pregnancy with a live embryo.
MedLine Citation:
PMID:  1451894     Owner:  NLM     Status:  MEDLINE    
Two cases with unsuccessful local and systemic methotrexate (MTX) therapy of tubal pregnancy with fetal heart rate activity are reported. The three modes of therapy, the first with local potassium chloride solution injection, the second with local MTX injection, and the third with systemic MTX injection, failed in the resolution of viable ectopic pregnancy. Therapy of MTX in cases of tubal pregnancy with demonstrable fetal heart rate beats, should be reconsidered.
D Bider; G Oelsner; D Admon; D Levran; M Goldenberg; S Mashiach
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  46     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1993-01-07     Completed Date:  1993-01-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  154-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
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MeSH Terms
Fetal Viability
Heart Rate, Fetal
Methotrexate / administration & dosage,  therapeutic use*
Potassium Chloride / therapeutic use
Pregnancy, Tubal / drug therapy*
Reg. No./Substance:
59-05-2/Methotrexate; 7447-40-7/Potassium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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