Document Detail

Unstudied infants: outcomes of moderately premature infants in the neonatal intensive care unit.
MedLine Citation:
PMID:  16611647     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Newborns of 30-34 weeks gestation comprise 3.9% of all live births in the United States and 32% of all premature infants. They have been studied much less than very low birthweight infants.
OBJECTIVE: To measure in-hospital outcomes and readmission within three months of discharge of moderately premature infants.
DESIGN: Prospective cohort study including retrospective chart review and telephone interviews after discharge.
SETTING: Ten birth hospitals in California and Massachusetts.
PATIENTS: Surviving moderately premature infants born between October 2001 and February 2003.
MAIN OUTCOME MEASURES: (a) Occurrence of assisted ventilation during the hospital stay after birth; (b) adverse in-hospital outcomes-for example, necrotising enterocolitis; (c) readmission within three months of discharge.
RESULTS: With the use of prospective cluster sampling, 850 eligible infants and their families were identified, randomly selected, and enrolled. A total of 677 families completed a telephone interview three months after hospital discharge. During the birth stay, these babies experienced substantial morbidity: 45.7% experienced assisted ventilation, and 3.2% still required supplemental oxygen at 36 weeks. Readmission within three months occurred in 11.2% of the cohort and was higher among male infants and those with chronic lung disease.
CONCLUSIONS: Moderately premature infants experience significant morbidity, as evidenced by high rates of assisted ventilation, use of oxygen at 36 weeks, and readmission. Such morbidity deserves more research.
G J Escobar; M C McCormick; J A F Zupancic; K Coleman-Phox; M A Armstrong; J D Greene; E C Eichenwald; D K Richardson
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, U.S. Gov't, P.H.S.     Date:  2006-04-12
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  91     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-06-22     Completed Date:  2006-08-09     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  England    
Other Details:
Languages:  eng     Pagination:  F238-44     Citation Subset:  AIM; IM    
Kaiser Permanente Medical Care Program, Division of Research, Perinatal Research Unit, Oakland, CA 94612, USA.
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MeSH Terms
Birth Weight
Epidemiologic Methods
Gestational Age
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / therapy*
Intensive Care, Neonatal* / methods
Oxygen Inhalation Therapy / utilization
Patient Readmission / statistics & numerical data
Respiration, Artificial / utilization
Treatment Outcome
Grant Support
5 R01 HS 10131-02/HS/AHRQ HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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