Document Detail

Unstable angina: relationship of clinical presentation, coronary artery pathology, and clinical outcome.
MedLine Citation:
PMID:  8435924     Owner:  NLM     Status:  MEDLINE    
Patients with unstable angina are heterogeneous with respect to presentation, coronary artery morphology, and clinical outcome. Subclassification of these patients based on clinical history has been proposed as a means of identifying individuals at increased cardiac risk. We applied such a classification system to 129 patients discharged from a coronary care unit with a diagnosis of acute myocardial ischemia. Patients were then assessed for cardiac events (recurrent angina requiring revascularization, myocardial infarction, death) 12 months following hospital discharge. Patients were classified as recent onset unstable angina preinfarction (n = 42), crescendo unstable angina preinfarction (n = 48), and unstable angina postinfarction (n = 39). Within each of these groups, the patients were further subclassified based on the occurrence of angina on effort, at rest, or both. No attempt was made to subset patients taking anti-ischemic drugs at the time of clinical presentation to the physician. Coronary angiographic pathology (morphology and number of vessels involved) was similar in the subgroups, but coronary artery thrombus was statistically more likely to be found in patients with crescendo rest angina preinfarction or with frequent anginal episodes at rest postinfarction. Mortality was significantly higher for patients with unstable angina postinfarction (7.7%) than preinfarction (1.1%). No statistical differences were noted between the subgroups with respect to the occurrence of myocardial infarction or recurrent unstable angina requiring revascularization. These data suggest that subclassification of unstable angina patients based on clinical characteristics at presentation is not useful to predict subsequent myocardial infarction or recurrent angina requiring revascularization.(ABSTRACT TRUNCATED AT 250 WORDS)
B D Bertolet; J Dinerman; R Hartke; C R Conti
Related Documents :
7326734 - The role of intra-aortic balloon pump in the management of patients with main left coro...
10603514 - Pathology of unstable angina: analysis of biopsies obtained by directional coronary ath...
18609054 - Refractory angina pectoris carries a favourable prognosis: a three-year follow-up of 15...
9120664 - Clinical pharmacology of calcium antagonists as antihypertensive and anti-anginal drugs.
7082084 - Closed mitral valvotomy: actuarial analysis of results in 654 patients over 12 years an...
3677494 - Analysis of ambulatory electrocardiograms in 14 patients who experienced sudden cardiac...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  16     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-03-25     Completed Date:  1993-03-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  116-22     Citation Subset:  IM    
Department of Medicine, University of Florida College of Medicine, Gainesville, Florida.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Angina, Unstable / classification*,  etiology,  pathology
Coronary Disease / complications,  pathology
Coronary Vessels / pathology*
Death, Sudden, Cardiac / epidemiology
Follow-Up Studies
Middle Aged
Myocardial Infarction / complications,  epidemiology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Ventricular arrhythmias in patients recovering from myocardial infarction: do residual myocardial is...
Next Document:  Differences of intravenous nitroglycerin responses in left ventricular systolic and end-diastolic pr...