Document Detail

Unstable angina following anaphylaxis.
MedLine Citation:
PMID:  19201942     Owner:  NLM     Status:  MEDLINE    
A 55-year-old woman developed unstable angina following an episode of severe anaphylaxis which was treated with 0.5 mg intramuscular epinephrine (adrenaline). The exact cause of her ongoing unstable angina was uncertain but may have reflected either vasospasm superimposed upon an area of atherosclerotic coronary disease, or vasospasm induced plaque rupture. Four weeks later, she had a second episode of anaphylaxis, and suffered a cardiac arrest after receiving a bolus of intravenous epinephrine. This case illustrates the importance of careful assessment of patients after anaphylaxis, both to prevent recurrence and to treat complications from the episode. It highlights the dangers of intravenous epinephrine in treating anaphylaxis outside anaesthetic and intensively monitored settings.
R Ameratunga; M Webster; H Patel
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  84     ISSN:  1469-0756     ISO Abbreviation:  Postgrad Med J     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-04-06     Revised Date:  2009-10-22    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  659-61     Citation Subset:  IM    
Associate Department of Clinical Immunology, Auckland City Hospital, Park Road, Grafton, Auckland 1001, New Zealand.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anaphylaxis / drug therapy,  etiology*
Angina, Unstable / etiology*
Coronary Vasospasm / etiology
Epinephrine / administration & dosage*
Food Hypersensitivity*
Heart Arrest / etiology
Injections, Intramuscular
Injections, Intravenous
Middle Aged
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Longitudinal study of Chinese patients with pernicious anaemia.
Next Document:  Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis.