Document Detail

Unruptured intracranial aneurysms: natural history and clinical management. Update on the international study of unruptured intracranial aneurysms.
MedLine Citation:
PMID:  16935706     Owner:  NLM     Status:  MEDLINE    
In guiding treatment decisions for all patients with unruptured intracranial aneurysms, it is important to compare size-, site-, and group-specific natural history data with size-, site- and age-specific treatment morbidity and mortality data. Because patient age has a major effect on operative morbidity and mortality, but relatively little effect on natural history, surgical treatment of an UIA patient over age 50 and any treatment of UIA patients over age 70 should be considered with particular vigilance. Optimally, patients should be evaluated and treated at high-volume centers in a setting that emphasizes neurovascular teamwork and unbiased presentation and delivery of different therapeutic option, including the option of observation, which is often appropriate for patients with UIAs.
David O Wiebers
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neuroimaging clinics of North America     Volume:  16     ISSN:  1052-5149     ISO Abbreviation:  Neuroimaging Clin. N. Am.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-28     Completed Date:  2006-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211377     Medline TA:  Neuroimaging Clin N Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  383-90, vii     Citation Subset:  IM    
Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA.
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MeSH Terms
Age Factors
Aneurysm, Ruptured / etiology*,  surgery
Intracranial Aneurysm / complications*,  pathology,  surgery
Pilot Projects
Risk Assessment
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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