Document Detail

Unresponsiveness of GH and cortisol to insulin-hypoglycemia in a patient with sub-total pancreatectomy.
MedLine Citation:
PMID:  6368209     Owner:  NLM     Status:  MEDLINE    
Responses of plasma growth hormone (GH) and cortisol to insulin-induced hypoglycemia were repeatedly examined during a therapy of diabetes mellitus in a sub-totally pancreatectomized patient. During a mild control period of diabetes mellitus without any hypoglycemic attacks, insulin-induced hypoglycemia evoked a remarkable increase in plasma GH as well as cortisol while neither GH nor cortisol responded to insulin hypoglycemia during the strict control period with frequent episodes of hypoglycemia. On the other hand, plasma GH and cortisol responses to all other endocrinological stimuli were normal. The mechanism of such impaired hormone secretion during the strict control period of diabetes mellitus in this patient remains unclear.
T Chiba; C Toda; Y Okimura; Y Matsuda; T Inatome; T Inoh; K Chihara; T Fujita
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Endocrinologia japonica     Volume:  30     ISSN:  0013-7219     ISO Abbreviation:  Endocrinol. Jpn.     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1984-04-27     Completed Date:  1984-04-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376546     Medline TA:  Endocrinol Jpn     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  571-5     Citation Subset:  IM    
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MeSH Terms
Glucagon / blood
Growth Hormone / secretion*
Hydrocortisone / secretion*
Hypoglycemia / metabolism*
Insulin / pharmacology*
Middle Aged
Reg. No./Substance:
11061-68-0/Insulin; 50-23-7/Hydrocortisone; 9002-72-6/Growth Hormone; 9007-92-5/Glucagon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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