Document Detail

Unraveling the pheromone biosynthesis activating neuropeptide (PBAN) signal transduction cascade that regulates sex pheromone production in moths.
MedLine Citation:
PMID:  20831957     Owner:  NLM     Status:  MEDLINE    
Studies over the past three decades have demonstrated that female moths usually produce sex pheromones as multicomponent blends in which the ratios of the individual components are precisely controlled, making it possible to generate species-specific pheromone blends. Most moth pheromone components are de novo synthesized from acetyl-CoA in the pheromone gland (PG) through modifications of fatty acid biosynthetic pathways. Pheromone biosynthesis activating neuropeptide (PBAN), a neurohormone produced by a cephalic organ (subesophageal ganglion) stimulates sex pheromone biosynthesis in the PG via an influx of extracellular Ca(2+). In recent years, we have expanded our knowledge of the precise mechanisms underlying silkmoth (Bombyx mori) sex pheromone production by characterizing a number of key molecules. In this review, we want to highlight our efforts in elucidating these mechanisms in B. mori and to understand how they relate more broadly to lepidopteran sex pheromone production in general.
Shogo Matsumoto; Atsushi Ohnishi; Jae Min Lee; J Joe Hull
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Vitamins and hormones     Volume:  83     ISSN:  0083-6729     ISO Abbreviation:  Vitam. Horm.     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-13     Completed Date:  2011-01-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413601     Medline TA:  Vitam Horm     Country:  United States    
Other Details:
Languages:  eng     Pagination:  425-45     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Molecular Entomology Laboratory, RIKEN Advanced Science Institute, Wako, Saitama, Japan.
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MeSH Terms
Bombyx / metabolism*
Insect Proteins / physiology*
Models, Biological
Neuropeptides / physiology*
Scent Glands / metabolism
Sex Attractants / metabolism*
Signal Transduction*
Reg. No./Substance:
0/Insect Proteins; 0/Neuropeptides; 0/Sex Attractants; 0/pheromone biosynthesis activating neuropeptide, Helicoverpa zea

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