| Unnatural history of the right ventricle in patients with congenitally malformed hearts. | |
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MedLine Citation:
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PMID: 21087566 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The long-term outcome of patients with congenitally malformed hearts involving abnormal right ventricular morphology and haemodynamics is variable. In most instances, the patients are at risk for right ventricular failure, in part due to morphological differences between the right and left ventricles and their response to chronic volume and pressure overload. In patients after repair of tetralogy of Fallot, and after balloon valvotomy for valvar pulmonary stenosis, pulmonary regurgitation is the most significant risk factor for right ventricular dysfunction. In patients with a dominant right ventricle after Fontan palliation, and in those with systemic right ventricles in association with surgically or congenitally corrected transposition, the right ventricle is not morphologically capable of dealing with chronic exposure to the high afterload of the systemic circulation. In patients with Ebstein's malformation of the tricuspid valve, the degree of atrialisation of the right ventricle determines how well the right ventricle will function as the pump for the pulmonary vascular bed. |
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Authors:
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Leo Lopez; Meryl S Cohen; Robert H Anderson; Andrew N Redington; David G Nykanen; Daniel J Penny; John E Deanfield; Benjamin W Eidem |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cardiology in the young Volume: 20 Suppl 3 ISSN: 1467-1107 ISO Abbreviation: Cardiol Young Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9200019 Medline TA: Cardiol Young Country: England |
Other Details:
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Languages: eng Pagination: 107-12 Citation Subset: IM |
Affiliation:
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Division of Pediatric Cardiology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York, United States of America. llmd@llmd.net |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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