Document Detail


Universal Caging Group for the in-Cell Detection of Glutathione Transferase Applied to (19) F NMR and Bioluminogenic Probes.
MedLine Citation:
PMID:  22689392     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Probing another way: As glutathione transferases (GSTs) are overexpressed in certain tumours and are used as fusion partners, GST detection methods can be used in cancer diagnosis or protein microanalysis. We describe the design of (19) F NMR and bioluminescence probes of GST activity by using the universal caging group. The probes were successfully applied in vitro and in living cells.
Authors:
Mika Ito; Aya Shibata; Jie Zhang; Michio Hiroshima; Yasushi Sako; Yukiko Nakano; Kyoko Kojima-Aikawa; Bengt Mannervik; Satoshi Shuto; Yoshihiro Ito; Ralf Morgenstern; Hiroshi Abe
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-11
Journal Detail:
Title:  Chembiochem : a European journal of chemical biology     Volume:  -     ISSN:  1439-7633     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100937360     Medline TA:  Chembiochem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute, 2-1, Hirosawa, Wako-Shi, Saitama 351-0198 (Japan); Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo-Shi, Hokkaido 060-0812 (Japan).
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