Document Detail


United airways: the impact of chronic rhinosinusitis and nasal polyps in bronchiectasic patient's quality of life.
MedLine Citation:
PMID:  19772517     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The nose and the bronchi belong, in anatomical and physiopathological terms, to the concept of united airways. Associations between upper and lower airways diseases have been demonstrated in allergic rhinitis and asthma, nasal polyposis (NP) and asthma, chronic rhinosinusitis (CRS) and chronic obstructive pulmonary disease, and more recently CRS/NP and bronchiectasis (BQ). OBJECTIVE: To evaluate the impact of CRS on quality of life (QoL) of patients with BQ, and to correlate these findings with the pulmonary status, nasal symptoms, and general health status. METHODS: In a prospective study, patients with BQ (n = 80) were evaluated for CRS and NP using EP(3)OS criteria, and severity of BQ using chest high resolution computed tomography (HRCT)-scan. Quality of life was assessed in all patients by using specific [Sinonasal Outcome Test-20 (SNOT-20), St George Respiratory Questionnaire (SGRQ)], and generic (Short Form-36; SF-36) questionnaires. RESULTS: Using SNOT-20, patients with CRS had worse QoL (2.1 +/- 0.1; P < 0.001) than patients without CRS (0.4 +/- 0.06). Using SGRQ total score, patients with CRS had worse QoL (43.7 +/- 2.2; P < 0.001) than patients without CRS (24.7 +/- 2.5). Using SF-36, patients with CRS had worse QoL, both in the physical summary (64 +/- 3.4; P < 0.05) and the mental summary (65.5 +/- 4.7; P < 0.05), than patients without CRS (physical summary [PS]: 76.2 +/- 3.3; mental summary [MS]: 78.3 +/- 5.3, respectively). Sinonasal Outcome Test-20 was correlated with SGRQ total score (r = 0.72; P < 0.01), and SF-36 physical summary (r = -0.63; P < 0.01). St George Respiratory Questionnaire was correlated with SF-36 on physical summary (r = -0.58; P < 0.05) and with forced expiratory volume in 1 s (r = -0.41; P < 0.05). CONCLUSION: These results suggested that CRS, measured by both specific and generic questionnaires, has a considerable impact on the QoL of patients with BQ.
Authors:
J M Guilemany; J Angrill; I Alobid; S Centellas; E Prades; J Roca; L Pujols; M Bernal-Sprekelsen; C Picado; J Mullol
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Allergy     Volume:  64     ISSN:  1398-9995     ISO Abbreviation:  Allergy     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-23     Completed Date:  2010-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804028     Medline TA:  Allergy     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  1524-9     Citation Subset:  IM    
Affiliation:
Rhinology Unit and Smell Clinic, Department of Otorhinolaryngology, Hospital Cl??nic i Universitari, Barcelona, Spain.
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MeSH Terms
Descriptor/Qualifier:
Bronchiectasis / complications*,  diagnosis
Chronic Disease
Female
Humans
Male
Middle Aged
Nasal Polyps / complications*,  diagnosis
Quality of Life*
Questionnaires
Rhinitis / complications*,  diagnosis,  physiopathology
Sinusitis / complications*,  diagnosis,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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