Document Detail

Unintentional fatal phosphine gas poisoning of a family.
MedLine Citation:
PMID:  21926889     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The objective of the study was to report the toxicity of phosphine gas after a residential fumigation that resulted in fatal poisoning of a 15-month-old toddler and her 4-year-old sibling.
METHODS: This is a case report and a review of literature.
RESULTS: A family of 6 members was exposed to phosphine gas after their yard was treated with aluminum phosphide for a rodent infestation. The inhalation of phosphine gas initially caused symptoms of abdominal distress in all of the family members. Within 36 hours of exposure, the 4-year-old sibling died of cardiopulmonary failure in a local emergency department. After an initial presentation of respiratory distress, the 15-month-old toddler progressed to complete cardiopulmonary collapse and did not survive despite aggressive intervention including extracorporeal membrane life support.
CONCLUSIONS: Unintentional phosphine gas exposure is rare but has a toxic profile that results in a high fatality rate with no known antidote.
Tara J Lemoine; Kristin Schoolman; Geoffrey Jackman; Donald D Vernon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric emergency care     Volume:  27     ISSN:  1535-1815     ISO Abbreviation:  Pediatr Emerg Care     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-19     Completed Date:  2012-01-17     Revised Date:  2012-02-08    
Medline Journal Info:
Nlm Unique ID:  8507560     Medline TA:  Pediatr Emerg Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  869-71     Citation Subset:  IM    
Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Utah, Salt Lake City, UT, USA.
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MeSH Terms
Accidents, Home*
Aluminum Compounds / poisoning*
Child, Preschool
Diagnostic Errors*
Diarrhea / chemically induced
Fatal Outcome
Foodborne Diseases / diagnosis
Heart Arrest / chemically induced*,  therapy
Nausea / chemically induced
Phosphines / poisoning*
Rodenticides / poisoning*
Vomiting / chemically induced
Reg. No./Substance:
0/Aluminum Compounds; 0/Gases; 0/Phosphines; 0/Rodenticides; 20859-73-8/aluminum phosphide
Comment In:
Pediatr Emerg Care. 2012 Jan;28(1):98   [PMID:  22217899 ]

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