Document Detail


Unilesional follicular mycosis fungoides: report of two cases with progression to tumor stage and review of the literature.
MedLine Citation:
PMID:  22882174     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Mycosis fungoides (MF) is the most common type of cutaneous lymphoma and has protean clinicopathological manifestations. Follicular or folliculotropic MF (FMF) is a rare variant, which histopathologically is characterized by pronounced folliculotropism of neoplastic T cells, with or without follicular mucinosis, and clinically by an impaired prognosis compared to classic MF. In contrast, unilesional MF is a very rare variant with an excellent prognosis, with a single case of large-cell transformation reported to date. The combination of folliculotropic and unilesional MF is very unusual, with only two cases reported to date. Here we report two patients with unilesional folliculotropic MF with progression to tumor stage in both patients. To the best of our knowledge, this is the first report on the disease evolution with large-cell transformation and progression of unilesional FMF. Complete remission was achieved by local radiation therapy in both patients. The differential diagnoses, classification and implications for the treatment of unilesional FMF as well as the pertinent literature are discussed.
Authors:
Werner Kempf; Dmitry V Kazakov; Martin Schermesser; Stanislav A Buechner; Laurent Parmentier; Anja Wysocki; Gabriele Palmedo; Peter Häusermann
Related Documents :
23119614 - Endoscopic dacryocystorhinostomy and retrograde nasolacrimal duct dilatation with cannu...
22647824 - Disseminated cysticercosis incidentally diagnosed in a patient of low backache: a case ...
22767304 - Myopericarditis during a primary epstein-barr virus infection in an otherwise young adu...
11772694 - Clinicopathological validation study of four sets of clinical criteria for vascular dem...
22687684 - Tongue swelling in association with oseltamivir (tamiflu).
11928784 - Accidental ingestion of cotton bud stick during alcohol intoxication: an unusual cause ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-9
Journal Detail:
Title:  Journal of cutaneous pathology     Volume:  -     ISSN:  1600-0560     ISO Abbreviation:  J. Cutan. Pathol.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0425124     Medline TA:  J Cutan Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 John Wiley & Sons A/S.
Affiliation:
Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Niobium pentoxide as a new filler for methacrylate-based root canal sealers.
Next Document:  Validation of the exercise addiction inventory in a Danish sport context.