Document Detail


Unilateral testicular torsion: protective effect of verapamil on contralateral testicular histology.
MedLine Citation:
PMID:  10529667     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this experimental study, it was our aim to reduce the effects of ischemic insults to the contralateral testicle after unilateral testicular torsion. The protective effect of a calcium channel blocking agent (verapamil) on the histology and the tubular diameter of contralateral testicle was evaluated. Following a definite period of unilateral testicular torsion (i.e., 4 h), the protective effect of this specific medication was evaluated both after detorsion and orchiectomy procedures. The results of our study demonstrated the protective effect of verapamil on both parameters, especially in animals undergoing orchiectomy. The majority of the specimens demonstrated normal histologic findings together with preserved tubular structures after a 1-week period under verapamil medication.
Authors:
K Sarica; K Bakir; F Yagci; A Erbagci; O Topcu; O Uysal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Urologia internationalis     Volume:  62     ISSN:  0042-1138     ISO Abbreviation:  Urol. Int.     Publication Date:  1999  
Date Detail:
Created Date:  1999-12-21     Completed Date:  1999-12-21     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0417373     Medline TA:  Urol Int     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  159-63     Citation Subset:  IM    
Affiliation:
Department of Urology, Sahinbey Hospital, University of Gaziantep Medical School, Gaziantep, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Animals
Calcium Channel Blockers / pharmacology*
Male
Orchiectomy
Rats
Rats, Wistar
Spermatic Cord Torsion / drug therapy*,  pathology,  surgery
Testis / blood supply,  pathology*
Verapamil / pharmacology*
Chemical
Reg. No./Substance:
0/Calcium Channel Blockers; 52-53-9/Verapamil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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