Document Detail


Unilateral seizures in a patient with hairy cell leukemia treated with interferon.
MedLine Citation:
PMID:  3931949     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A patient is described who developed unilateral seizures whilst being treated with recombinant interferon for hairy cell leukemia. Special features included the relatively low dose of interferon, the focal aspect of the epilepsy and the high resistance to anticonvulsants. Oligoclonal banding of cerebrospinal fluid proteins may have resulted from polyclonal activation of bone marrow plasma cells during interferon treatment. Disturbances of consciousness, dysphasia, visual hallucinations, upper motor neuron deficit, tremor, dizziness, numbness, myalgia and headache, all of them neurological complications of interferon treatment, are discussed.
Authors:
R A Dierckx; A Michotte; E Schmedding; G Ebinger; T Degeeter; B van Camp
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  87     ISSN:  0303-8467     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  1985  
Date Detail:
Created Date:  1985-12-16     Completed Date:  1985-12-16     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  209-12     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Epilepsies, Partial / etiology*
Humans
Interferon-gamma / adverse effects*
Leukemia, Hairy Cell / therapy*
Male
Chemical
Reg. No./Substance:
82115-62-6/Interferon-gamma

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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