| Unilateral salpingo-oophorectomy as fertility-sparing surgery for borderline ovarian tumors. | |
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MedLine Citation:
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PMID: 21621167 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: To investigate recurrence rates and fertility outcomes of patients with borderline ovarian tumors (BOTs) treated with fertility-sparing surgery. METHODS: This was a retrospective study. All women with BOTs from 2000 to 2006 were evaluated. Clinical outcomes were compared among groups that underwent radical, unilateral salpingo-oophorectomy, or ovarian cystectomy. The effects of clinical characteristics on recurrence were analyzed by independent t test, chi-square test, and Cox proportional hazard model. RESULTS: After a mean follow-up period of 56.5 months, all 61 patients were alive. Seven (11.5%) had developed disease recurrence, and all were in the fertility-sparing group. Of these, five were in the cystectomy-only group and two in the unilateral salpingo-oophorectomy group. There was significant difference in tumor recurrence rates between the two groups (hazard ratio: 0.26, 95% confidence interval: 0.11-0.61). Nine pregnancies were achieved in six women, resulting in five deliveries CONCLUSION: Fertility-sparing surgery is an acceptable and safe option for women with BOTs who wish to preserve fertility. Unilateral salpingo-oophorectomy must be considered as the first choice. |
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Authors:
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Hsiao-Wen Tsai; Chin-Chu Ko; Chang-Ching Yeh; Yi-Jen Chen; Nae-Fang Twu; Kuan-Chong Chao; Ming-Shyen Yen |
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Publication Detail:
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Type: Journal Article Date: 2011-05-12 |
Journal Detail:
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Title: Journal of the Chinese Medical Association : JCMA Volume: 74 ISSN: 1728-7731 ISO Abbreviation: J Chin Med Assoc Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-05-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101174817 Medline TA: J Chin Med Assoc Country: China (Republic : 1949- ) |
Other Details:
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Languages: eng Pagination: 250-4 Citation Subset: IM |
Copyright Information:
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Copyright © 2011. Published by Elsevier B.V. |
Affiliation:
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Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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