Document Detail

Unilateral nephrectomy as palliative therapy in an infant with autosomal recessive polycystic kidney disease.
MedLine Citation:
PMID:  15540776     Owner:  NLM     Status:  MEDLINE    
Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD) implies a dire prognosis. Neonates affected by the more severe variants of ARPKD suffer respiratory failure caused by massive kidneys that restrict diaphragmatic expansion and result in pulmonary hypoplasia. Afflicted infants who survive the neonatal period and gain adequate respiratory function may subsequently suffer from an inability to tolerate enteral nutrition due to abdominal compression from the massive kidney and the systemic effects of renal compromise. Palliative unilateral or bilateral nephrectomy may be considered in rare instances to facilitate pulmonary expansion and gastrointestinal function. We report on an infant with severe ARPKD who was able to tolerate enteral nutrition only after left nephrectomy.
Aseem R Shukla; Darcie A Kiddoo; Douglas A Canning
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  172     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-11-15     Completed Date:  2005-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2000-1     Citation Subset:  AIM; IM    
Division of Pediatric Urology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104-4399, USA.
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MeSH Terms
Infant, Newborn
Nephrectomy / methods*
Palliative Care
Polycystic Kidney, Autosomal Recessive / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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