| Unilateral hyperfusion in brain-perfusion SPECT predicts poor prognosis in acute encephalitis. | |
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MedLine Citation:
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PMID: 9153471 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied 88 patients with acute encephalitis using hexamethylpropyleneamine oxime and single photon emission computed tomography (SPECT). All patients had been initially treated with intravenous acyclovir. The etiology could be disclosed in 37 patients (42%), which included 15 patients with herpes simplex encephalitis, 7 with varicella-zoster encephalitis, and 29 with other encephalitides (Mycoplasma, adenovirus, influenza, rotavirus, rubella, Epstein-Barr, arbovirus, syphilis, and tuberculosis). Unilateral hyperperfusion in SPECT was an independent predictor of poor prognosis, whereas neither clinical outcome variables, such as seizures, state of consciousness, and focal neurologic findings, nor CSF or EEG findings were not. Focal unilateral hyperperfusion is an indicator of severe inflammation of the brain tissue and predicts a poor outcome as assessed in terms of activities of daily living after recovery. |
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Authors:
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J Launes; J Sirén; L Valanne; O Salonen; P Nikkinen; A M Seppäläinen; K Liewendahl |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurology Volume: 48 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 1997 May |
Date Detail:
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Created Date: 1997-06-11 Completed Date: 1997-06-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1347-51 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurology, Helsinki University Central Hospital, Finland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Brain / radionuclide imaging* Cerebrovascular Circulation* Encephalitis / diagnosis, physiopathology*, radionuclide imaging* Female Humans Magnetic Resonance Imaging Male Middle Aged Models, Theoretical Prognosis Regression Analysis Tomography, Emission-Computed, Single-Photon* Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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