Document Detail


Unilateral cerebral polymicrogyria with ipsilateral cerebral hemiatrophy.
MedLine Citation:
PMID:  12271397     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated six children in whom MR imaging showed unilateral cerebral polymicrogyria associated with ipsilateral cerebral atrophy and ipsilateral brain stem atrophy. The aim of this study was to clarify whether this disorder based on neuroimaging constitutes a new homogeneous clinical entity. The subjects were six children whose ages at the time of MR imaging ranged from 8 months to 11 years. Their clinical and MR features were analyzed. All of the children were born between 38 and 42 weeks gestation, without any significant perinatal events. Spastic hemiplegia and epilepsy were observed in all of the patients, and mental retardation was observed in four. The MR findings included unilateral cerebral polymicrogyria associated with ipsilateral cerebral hemiatrophy and ipsilateral brain stem atrophy in all patients. The ipsilateral sylvian fissure was hypoplastic in four patients. These patients showed relatively homogeneous clinical and neuroimaging features. Although the additional clinical features varied according to the site and the extent affected by the polymicrogyria, this disorder could constitute a new relatively homogeneous clinical entity.
Authors:
Katsumi Hayakawa; Toyoko Kanda; Yuriko Yamori
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Publication Detail:
Type:  Journal Article     Date:  2002-04-17
Journal Detail:
Title:  European radiology     Volume:  12     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-09-24     Completed Date:  2003-02-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2542-7     Citation Subset:  IM    
Affiliation:
Department of Radiology, Kyoto City Hospital, 1-2 Higashi-Takada-cho, Mibu, Nakagyo-ku, 604-8845 Kyoto, Japan. khayaka@h4.dion.ne.jp
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MeSH Terms
Descriptor/Qualifier:
Brain Diseases / complications,  congenital,  diagnosis*
Cerebral Cortex / abnormalities*
Child
Child, Preschool
Epilepsy / congenital
Female
Hemiplegia / congenital
Humans
Infant
Magnetic Resonance Imaging
Male
Mental Retardation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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