Document Detail


Unilateral cerebellar aplasia.
MedLine Citation:
PMID:  8677027     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe three children with unilateral cerebellar aplasia (UCA). Deliveries at term and neonatal periods were uneventful. Pregnancy was normal in one and complicated by mild bleeding (in second and fourth month respectively) in two instances. Presenting signs were delayed motor development with marked contralateral torticollis (n = 1), hemiplegia (n = 1) and unusual head nodding (n = 1). Neuroradiological investigations revealed complete aplasia (n = 1) and subtotal aplasia (n = 2) of one cerebellar hemisphere with only a residual wing-like structure below the tentorium. There was contralateral underdevelopment of the brainstem. The infant with hemiplegic cerebral palsy had an additional supratentorial periventricular parenchymal defect, contralateral to the cerebellar hypoplasia. In view of literature reports, describing similar neuroradiological or neuropathological findings in asymptomatic individuals, it is doubtful whether UCA is responsible for our patient's problems. In our cases UCA has presumably resulted from a prenatal destructive lesion, possibly an infarct, but the timing and exact nature are unknown.
Authors:
E Boltshauser; M Steinlin; E Martin; T Deonna
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuropediatrics     Volume:  27     ISSN:  0174-304X     ISO Abbreviation:  Neuropediatrics     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-08-15     Completed Date:  1996-08-15     Revised Date:  2008-01-16    
Medline Journal Info:
Nlm Unique ID:  8101187     Medline TA:  Neuropediatrics     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  50-3     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Universities of Zuerich, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Brain Ischemia / physiopathology*
Cerebellum / abnormalities*
Developmental Disabilities / complications,  diagnosis
Female
Hemiplegia / complications
Humans
Infant
Magnetic Resonance Imaging
Male
Pregnancy
Pregnancy Complications
Tomography, X-Ray Computed
Torticollis / complications,  diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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