Document Detail

Uniform yeast cell assembly via microfluidics.
MedLine Citation:
PMID:  22655026     Owner:  NLM     Status:  PubMed-not-MEDLINE    
This paper reports the use of microfluidic approaches for the fabrication of yeastosomes (yeast-celloidosomes) based on self-assembly of yeast cells onto liquid-solid or liquid-gas interfaces. Precise control over fluidic flows in droplet- and bubble-forming microfluidic devices allows production of monodispersed, size-selected templates. The general strategy to organize and assemble living cells is to tune electrostatic attractions between the template (gel or gas core) and the cells via surface charging. Layer-by-Layer (LbL) polyelectrolyte deposition was employed to invert or enhance charges of solid surfaces. We demonstrated the ability to produce high-quality, monolayer-shelled yeastosome structures under proper conditions when sufficient electrostatic driving forces are present. The combination of microfluidic fabrication with cell self-assembly enables a versatile platform for designing synthetic hierarchy bio-structures.
Ya-Wen Chang; Peng He; Samantha M Marquez; Zhengdong Cheng
Related Documents :
24741306 - Methotrexate diethyl ester-loaded lipid-core nanocapsules in aqueous solution increased...
23754316 - Tetraspanin 1 promotes invasiveness of cervical cancer cells.
24173806 - Quirky interacts with strubbelig and pal of quirky to regulate cell growth anisotropy d...
24958106 - Cell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates pte...
10328346 - Reproductive performance of bulls divergently selected on the basis of blood serum insu...
6427066 - Modification of cell growth and longevity using an in vivo assay in drosophila melanoga...
Publication Detail:
Type:  Journal Article     Date:  2012-05-08
Journal Detail:
Title:  Biomicrofluidics     Volume:  6     ISSN:  1932-1058     ISO Abbreviation:  Biomicrofluidics     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-01     Completed Date:  2012-08-23     Revised Date:  2013-02-26    
Medline Journal Info:
Nlm Unique ID:  101293825     Medline TA:  Biomicrofluidics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  24118-241189     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Electronic detection of dielectrophoretic forces exerted on particles flowing over interdigitated el...
Next Document:  Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mito...